Description

4-Piperidinemethanol, 1-(2,2,2-Trifluoroethyl)- is a specialized piperidine derivative featuring a trifluoroethyl substituent, which imparts unique physicochemical properties critical for advanced synthesis. This compound serves as a high-value pharmaceutical intermediate and key building block in the development of novel active ingredients. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and fine chemical sectors seeking to incorporate fluorine-containing motifs into their molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder drugs.
• Agrochemical Synthesis: Used as a building block for developing novel pesticides and herbicides, where the trifluoroethyl group can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a scaffold for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on the introduction and behavior of fluorine atoms in complex molecules.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects requiring specific, high-purity piperidine derivatives.

Basic Information

Product Name	4-Piperidinemethanol, 1-(2,2,2-Trifluoroethyl)-
CAS No.	831169-69-8
Molecular Formula	C8H14F3NO
Molecular Weight	197.20 g/mol
Synonyms	1-(2,2,2-Trifluoroethyl)-4-piperidinemethanol; 1-(Trifluoroethyl)-4-piperidinemethanol; 4-(Hydroxymethyl)-1-(2,2,2-trifluoroethyl)piperidine; (1-(2,2,2-Trifluoroethyl)piperidin-4-yl)methanol; 1-Trifluoroethyl-4-piperidinemethanol; 4-Piperidinemethanol, 1-(trifluoroethyl)-; 1-(2,2,2-Trifluoroethyl)-4-piperidinylmethanol
EINECS	Contact for details

Quality Control

Our production of 4-Piperidinemethanol, 1-(2,2,2-Trifluoroethyl)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets exacting customer specifications. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to support regulatory filings in pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.