Description

tert-Butyl 4-[(3-Chlorophenyl)Carbonyl]Piperazine-1-Carboxylate is a high-value, protected piperazine derivative and a key synthetic intermediate in modern organic chemistry. Its core value lies in its versatile piperazine scaffold and protected amine functionality, enabling the efficient synthesis of complex molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the construction of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its piperazine core for bioactivity.
• Chemical Synthesis: Serves as a versatile precursor for introducing the 3-chlorobenzoyl-piperazine moiety into more complex molecular architectures.
• Library Synthesis: Employed in parallel and combinatorial chemistry for generating diverse compound libraries for high-throughput screening.
• Process Chemistry: Used in route scouting and optimization for the scalable production of fine chemicals and APIs.
• Academic Research: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry programs at universities and institutes.

Basic Information

Product Name	tert-Butyl 4-[(3-Chlorophenyl)Carbonyl]Piperazine-1-Carboxylate
CAS No.	828299-83-8
Molecular Formula	C16H21ClN2O3
Molecular Weight	324.80 g/mol
Synonyms	1-Boc-4-(3-chlorobenzoyl)piperazine; tert-Butyl 4-(3-chlorobenzoyl)piperazine-1-carboxylate; 4-(3-Chlorobenzoyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(3-chlorobenzoyl)piperazine; 828299-83-8; BOC-4-(3-Chlorobenzoyl)piperazine; 4-(3-Chlorobenzoyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[(3-Chlorophenyl)Carbonyl]Piperazine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.