Description

tert-Butyl Piperazin-1-Ylacetate Dihydrochloride is a high-purity, salt-form chemical intermediate of significant importance in modern synthetic chemistry. Its value lies in its role as a versatile building block for constructing complex molecular architectures, particularly in the pharmaceutical sector. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the piperazine moiety for biological activity.
• Chemical Synthesis: Serves as a protected precursor for introducing the piperazin-1-ylacetate functional group into more complex molecules under controlled conditions.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs) working on proprietary compounds.

Basic Information

Product Name	tert-Butyl Piperazin-1-Ylacetate Dihydrochloride
CAS No.	827614-56-2
Molecular Formula	C10H21Cl2N2O2
Molecular Weight	272.19 g/mol
Synonyms	1-Piperazineacetic acid, 1-(1,1-dimethylethyl) ester, dihydrochloride; tert-Butyl 2-(piperazin-1-yl)acetate dihydrochloride; 2-(Piperazin-1-yl)acetic acid tert-butyl ester dihydrochloride; 1-Boc-piperazin-2-yl-acetic acid dihydrochloride (common abbreviation); Piperazin-1-yl-acetic acid tert-butyl ester hydrochloride; tert-Butyl piperazinylacetate dihydrochloride; N-Boc-piperazine-2-acetic acid dihydrochloride
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl Piperazin-1-Ylacetate Dihydrochloride is produced and tested under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.