Description

5-Bromo-3-[(4-Fluorobenzyl)Amino]Pyrazin-2-Amine is a high-purity, functionalized pyrazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and building block for the development of novel active molecules. It is primarily utilized by research institutions and chemical manufacturers in the life sciences sector for drug discovery and process chemistry applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs, particularly in kinase inhibitor research.
• Agrochemical Research: Used as a building block for developing novel crop protection agents and herbicides due to its heterocyclic structure.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science: Serves as a monomer or functional additive in the development of specialty polymers and advanced organic electronic materials.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and scale-up development.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	5-Bromo-3-[(4-Fluorobenzyl)Amino]Pyrazin-2-Amine
CAS No.	827602-57-3
Molecular Formula	C11H10BrFN4
Molecular Weight	297.13 g/mol
Synonyms	5-Bromo-3-[(4-fluorobenzyl)amino]pyrazin-2-amine; 3-Amino-5-bromo-N-(4-fluorobenzyl)pyrazin-2-amine; 5-Bromo-N2-(4-fluorobenzyl)pyrazine-2,3-diamine; 827602-57-3; 5-Bromo-3-((4-fluorobenzyl)amino)pyrazin-2-amine; 2-Amino-5-bromo-3-[(4-fluorophenyl)methyl]aminopyrazine
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-3-[(4-Fluorobenzyl)Amino]Pyrazin-2-Amine adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.