Description

2-(Piperazin-1-yl)propionic acid ethyl ester is a versatile piperazine derivative and a key organic building block. This compound is valued for its role as a crucial intermediate in the synthesis of complex molecules, particularly in the pharmaceutical sector. It is primarily sought by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of drug candidates, particularly those targeting the central nervous system (CNS), as an antidepressant, antipsychotic, or anti-anxiety agent.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and fungicides where the piperazine moiety imparts specific biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the manufacture of complex specialty chemicals, dyes, and functional materials.
• Ligand and Catalyst Preparation: Can be utilized to synthesize chelating ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	2-(Piperazin-1-yl)propionic acid ethyl ester
CAS No.	824414-06-4
Molecular Formula	C9H18N2O2
Molecular Weight	186.25 g/mol
Synonyms	Ethyl 2-(piperazin-1-yl)propanoate; Ethyl 2-piperazin-1-ylpropionate; 1-Piperazinepropanoic acid, ethyl ester; Ethyl α-(1-piperazinyl)propionate; 2-(1-Piperazinyl)propionic Acid Ethyl Ester; NSC 796093; AKOS005258155
EINECS	Contact for details

Quality Control

Our 2-(Piperazin-1-yl)propionic acid ethyl ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.