Description

(4,4-Difluoropiperidin-Yl)Acetonitrile is a high-value, fluorinated piperidine derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring a difluorinated piperidine ring linked to an acetonitrile group, makes it an essential intermediate for constructing complex molecules with enhanced biological activity and metabolic stability. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atoms can improve compound lipophilicity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science: Potential building block for advanced polymers and liquid crystals, where the fluorine content can impart specific dielectric and surface properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	(4,4-Difluoropiperidin-Yl)Acetonitrile
CAS No.	824413-96-9
Molecular Formula	C7H10F2N2
Molecular Weight	160.17 g/mol
Synonyms	2-(4,4-Difluoropiperidin-1-yl)acetonitrile; 1-(Cyanomethyl)-4,4-difluoropiperidine; 4,4-Difluoro-1-piperidineacetonitrile; Acetonitrile, (4,4-difluoro-1-piperidinyl)-; (4,4-Difluoropiperidino)acetonitrile; 4,4-Difluoropiperidine-1-acetonitrile; 824413-96-9
EINECS	Contact for details

Quality Control

Our (4,4-Difluoropiperidin-Yl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.