Description

trans-4-Aminomethyl-3-Hydroxypiperidine is a high-purity, multifunctional piperidine derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring both amino and hydroxyl functional groups on the piperidine ring, makes it an invaluable intermediate for constructing complex molecules with high stereochemical control. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, including potential central nervous system (CNS) agents and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, particularly in neurological and psychiatric therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides requiring precise molecular architecture.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new synthetic methodologies and constructing complex heterocyclic frameworks.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals and high-value fine chemicals where stereochemistry is crucial.

Basic Information

Product Name	trans-4-Aminomethyl-3-Hydroxypiperidine
CAS No.	823226-03-5
Molecular Formula	C6H14N2O
Molecular Weight	130.19 g/mol
Synonyms	(3R,4S)-3-Hydroxy-4-(aminomethyl)piperidine; (3R,4S)-4-(Aminomethyl)piperidin-3-ol; trans-4-(Aminomethyl)piperidin-3-ol; 4-(Aminomethyl)-3-hydroxypiperidine; 3-Hydroxy-4-piperidinemethanamine; 823226-03-5; (3R,4S)-rel-4-(Aminomethyl)piperidin-3-ol
EINECS	Contact for details

Quality Control

Our trans-4-Aminomethyl-3-Hydroxypiperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.