Description

Pyrido[3',2':4,5]Pyrrolo[1,2-A]Pyrazine, 3-Fluoro-5,5A,6,7,8,9-Hexahydro-9-Methyl-, (5Ar,9R)- is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure and defined stereochemistry. This compound is of significant value in modern medicinal chemistry for its role as a key building block in the synthesis of novel, targeted therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new drug candidates, particularly within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral scaffold in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile building block for constructing complex molecular libraries in drug discovery programs.
• Oncology Drug Development: Employed in the synthesis of potential kinase inhibitors and other targeted cancer therapies.
• CNS-Active Compound Synthesis: A key precursor for developing novel compounds targeting neurological disorders.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the commercial manufacturing of candidate drugs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services.

Basic Information

Product Name	Pyrido[3',2':4,5]Pyrrolo[1,2-A]Pyrazine, 3-Fluoro-5,5A,6,7,8,9-Hexahydro-9-Methyl-, (5Ar,9R)-
CAS No.	823216-67-7
Molecular Formula	C13H14FN3
Molecular Weight	231.27 g/mol
Synonyms	(5aR,9R)-3-Fluoro-9-methyl-2,3,5a,6,7,8,9,9a-octahydro-1H-pyrido[3',2':4,5]pyrrolo[1,2-a]pyrazine; 3-Fluoro-9-methyl-2,3,5a,6,7,8,9,9a-octahydro-1H-pyrido[3',2':4,5]pyrrolo[1,2-a]pyrazine (5aR,9R)-; (5aR,9R)-3-Fluoro-9-methyl-2,3,5a,6,7,8,9,9a-octahydro-1H-pyrido[3',2':4,5]pyrrolo[1,2-a]pyrazine; CAS 823216-67-7; Fluorinated Pyridopyrrolopyrazine Derivative; Fused Tricyclic Amine Intermediate.
EINECS	Contact for details

Quality Control

Our Pyrido[3',2':4,5]Pyrrolo[1,2-A]Pyrazine intermediate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.