Description

2,5-Diazabicyclo[2.2.2]Octane-3,6-Dione,1,2,4-Trimethyl-,(1R,4R)-(9Ci) is a high-purity, stereochemically defined bicyclic diamide compound. This advanced pharmaceutical intermediate is valued for its rigid, three-dimensional scaffold, which is crucial for imparting specific biological activity and metabolic stability in drug molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, where its structural motif can contribute to target specificity.
• Ligand and Catalyst Development: Acts as a precursor or core structure for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probe: Employed in medicinal chemistry to create molecular probes for studying enzyme function and protein-protein interactions.
• Advanced Material Research: Investigated as a monomer or cross-linking agent for creating polymers with unique thermal and mechanical properties.

Basic Information

Product Name	2,5-Diazabicyclo[2.2.2]Octane-3,6-Dione,1,2,4-Trimethyl-,(1R,4R)-(9Ci)
CAS No.	817575-51-2
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	(1R,4R)-1,2,4-Trimethyl-2,5-diazabicyclo[2.2.2]octane-3,6-dione; (1R,4R)-1,2,4-Trimethyl-3,6-dioxo-2,5-diazabicyclo[2.2.2]octane; 1,2,4-Trimethyl-2,5-diazabicyclo[2.2.2]octane-3,6-dione, (1R,4R)-; (1R,4R)-1,2,4-Trimethyl-DABCO-3,6-dione; (1R,4R)-TMDABCOdione; Chiral TMDABCO dione; 817575-51-2
EINECS	Contact for details

Quality Control

Our 2,5-Diazabicyclo[2.2.2]Octane-3,6-Dione,1,2,4-Trimethyl-,(1R,4R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting R&D and cGMP standards for advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.