Description

1-(2-Fluoro-4-Trifluoromethyl-Phenyl)-Piperazine is a high-purity fluorinated piperazine derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both fluorine and a trifluoromethyl group, making it an essential intermediate for developing compounds with enhanced biological activity and metabolic stability. This product is primarily needed by pharmaceutical R&D and fine chemical manufacturers focused on creating new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and material science.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new chemical entities and reaction pathways involving fluorinated aromatics.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	1-(2-Fluoro-4-Trifluoromethyl-Phenyl)-Piperazine
CAS No.	817170-70-0
Molecular Formula	C11H12F4N2
Molecular Weight	248.22 g/mol
Synonyms	1-(2-Fluoro-4-(trifluoromethyl)phenyl)piperazine; 2-Fluoro-4-(trifluoromethyl)-1-piperazinobenzene; 2-Fluoro-α,α,α-trifluoro-p-tolylpiperazine; 1-(2-Fluoro-4-trifluoromethylphenyl)piperazine; 817170-70-0; 1-(2-Fluoro-4-(trifluoromethyl)phenyl)piperazine; Piperazine, 1-[2-fluoro-4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-4-Trifluoromethyl-Phenyl)-Piperazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.