Description

4-Amino-1-Cbz-Piperidine is a versatile and high-value piperidine derivative, primarily serving as a critical building block in advanced organic synthesis. Its core value lies in providing a protected amine functionality essential for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is indispensable for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), especially within the fields of central nervous system (CNS) therapeutics and oncology.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in CNS and oncology research pipelines.
• Peptidomimetic Chemistry: Used to introduce constrained, nitrogen-containing cyclic structures into peptide backbones to enhance stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Custom Synthesis Building Block: Employed in contract research and manufacturing (CRAM) for the custom synthesis of complex, high-value target molecules.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Agrochemical Research: Acts as an intermediate in the development of new crop protection agents and herbicides.

Basic Information

Product Name	4-Amino-1-Cbz-Piperidine
CAS No.	813412-36-1
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	1-Cbz-4-Aminopiperidine; 4-Amino-1-(benzyloxycarbonyl)piperidine; 1-(Benzyloxycarbonyl)-4-aminopiperidine; 4-Amino-N-Cbz-piperidine; Piperidine, 4-amino-1-[(phenylmethoxy)carbonyl]-; 4-Amino-1-carbobenzyloxypiperidine; N-Cbz-4-Aminopiperidine; 1-N-Carbobenzyloxy-4-aminopiperidine
EINECS	Contact for details

Quality Control

Our 4-Amino-1-Cbz-Piperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. Certificates of Analysis (COA) are available for every batch and provided upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.