Description

3-Amino-1-Cbz-Piperidine is a high-purity, protected piperidine derivative serving as a critical chiral building block in advanced organic synthesis. Its primary value lies in providing a versatile, nitrogen-containing scaffold for constructing complex pharmaceutical intermediates and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) drugs, protease inhibitors, and other bioactive molecules.
• Peptidomimetic Chemistry: Used in the design and synthesis of peptide analogs and constrained scaffolds to improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Custom Synthesis: A starting material for the contract manufacturing of bespoke, high-value chemical entities for client-specific projects.

Basic Information

Product Name	3-Amino-1-Cbz-Piperidine
CAS No.	813412-35-0
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	1-Cbz-3-Aminopiperidine; 1-[(Benzyloxy)carbonyl]-3-aminopiperidine; 3-Amino-1-(phenylmethoxy)carbonylpiperidine; 3-Amino-N-Cbz-piperidine; 3-Amino-1-carbobenzyloxypiperidine; Piperidine, 3-amino-1-[(phenylmethoxy)carbonyl]-; 1-Carbobenzyloxy-3-aminopiperidine
EINECS	Contact for details

Quality Control

Our 3-Amino-1-Cbz-Piperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical applications, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.