Description

3-{[(Piperazin-1-Yl)Acetyl]Amino}Pyridine Trihydrochloride, 1-{2-Oxo-2-[(Pyridin-3-Yl)Amino]Ethyl}Piperazine Trihydrochloride is a high-purity, non-nucleoside building block and key intermediate in modern pharmaceutical synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of targeted therapeutics. It is primarily required by research institutions and pharmaceutical companies engaged in the discovery and process development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and receptor antagonist research.
• Chemical Biology Research: Used as a versatile scaffold for probing protein-ligand interactions and developing chemical probes.
• Medicinal Chemistry: Serves as a core structure for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the commercial manufacturing of complex molecules.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value compounds for preclinical and clinical trials.

Basic Information

Product Name	3-{[(Piperazin-1-Yl)Acetyl]Amino}Pyridine Trihydrochloride, 1-{2-Oxo-2-[(Pyridin-3-Yl)Amino]Ethyl}Piperazine Trihydrochloride
CAS No.	808764-17-2
Molecular Formula	C11H17N5O • 3HCl
Molecular Weight	367.67 g/mol (Free base: 235.29 g/mol)
Synonyms	1-[2-Oxo-2-(pyridin-3-ylamino)ethyl]piperazine trihydrochloride; 3-[(2-Piperazin-1-yl-2-oxoethyl)amino]pyridine trihydrochloride; N-(Pyridin-3-yl)-2-(piperazin-1-yl)acetamide trihydrochloride; 3-[(Piperazin-1-ylacetyl)amino]pyridine trihydrochloride; 808764-17-2; UNII-9K8P8E9F8V; 9K8P8E9F8V
EINECS	Contact for details

Quality Control

Our 3-{[(Piperazin-1-Yl)Acetyl]Amino}Pyridine Trihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated or nitrogen-purged environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.