Description

3-(Piperazin-1-yl)Phenol Hydrochloride is a high-purity organic salt compound that serves as a critical building block in advanced chemical synthesis. Its value lies in providing a functionalized phenol-piperazine scaffold essential for constructing complex molecules with targeted biological activity. This intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers developing new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and psychiatric therapeutic areas.
• Agrochemical Research: Used in developing new generation pesticides and herbicides that require specific piperazine-based active components.
• Chemical Biology & Proteomics: Serves as a versatile linker or spacer molecule in the design of chemical probes and affinity tags.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers and advanced organic materials.
• Academic & Contract Research: Essential reagent for methodological development and discovery chemistry within research institutions and CROs.

Basic Information

Product Name	3-(Piperazin-1-yl)Phenol Hydrochloride
CAS No.	807624-37-9
Molecular Formula	C10H15N2O·HCl
Molecular Weight	214.70 g/mol
Synonyms	3-(1-Piperazinyl)phenol hydrochloride; 3-Piperazin-1-yl-phenol hydrochloride; Phenol, 3-(1-piperazinyl)-, hydrochloride (1:1); 1-(3-Hydroxyphenyl)piperazine hydrochloride; 3-Hydroxyphenylpiperazine hydrochloride; m-Hydroxyphenylpiperazine hydrochloride; 3-(Piperazin-1-yl)phenol HCl
EINECS	Contact for details

Quality Control

Our 3-(Piperazin-1-yl)Phenol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.