Description

Tricyclo[3.2.1.02,4]Octan-6-One, 3-(Hydroxymethyl)-, (1R,2R,3S,4S,5R)-Rel- (9Ci) is a highly functionalized, stereochemically defined bicyclic ketone derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique, rigid tricyclic core and defined stereochemistry make it invaluable for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Catalyst Ligand Precursor: Used to develop novel chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating stereochemically pure active ingredients in advanced crop protection agents.
• Academic & Industrial R&D: Employed in methodological studies and the exploration of new chemical space for material science and medicinal chemistry.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals requiring a specific, rigid molecular framework.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Tricyclo[3.2.1.02,4]Octan-6-One, 3-(Hydroxymethyl)-, (1R,2R,3S,4S,5R)-Rel- (9Ci)
CAS No.	802911-82-6
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	rel-(1R,2R,3S,4S,5R)-3-(Hydroxymethyl)tricyclo[3.2.1.02,4]octan-6-one; 3-(Hydroxymethyl)tricyclo[3.2.1.02,4]octan-6-one, (1R,2R,3S,4S,5R)-rel-; Bicyclo[2.2.2]octane derivative; Chiral Tricyclic Ketone Alcohol; (rel)-3-Hydroxymethyltricyclo[3.2.1.02,4]octan-6-one
EINECS	Contact for details

Quality Control

Every batch of our Tricyclo[3.2.1.02,4]Octan-6-One derivative is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, which is critical for sensitive asymmetric synthesis. Certificates of Analysis (COA) detailing specifications such as chiral purity (HPLC), assay, and impurity profile are available upon request and are aligned with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.