Description

Isonicotinoyl Chloride, 2-Chloro-6-Ethyl- (7Ci) is a specialized heterocyclic acid chloride derivative, serving as a critical high-purity building block in advanced organic synthesis. Its value lies in its reactive carbonyl chloride group, which enables efficient amide bond formation and the introduction of the isonicotinoyl moiety into complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where the 2-chloro-6-ethyl substituted pyridine scaffold is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing antimicrobial properties.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides that incorporate a substituted pyridine core for enhanced bioactivity.
• Ligand and Catalyst Development: Used to synthesize complex ligands for metal-organic frameworks (MOFs) or asymmetric catalysis.
• Material Science Research: Intermediate in the production of functional polymers or organic electronic materials with specific pyridine-based side chains.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific research and scale-up projects.

Basic Information

Product Name	Isonicotinoyl Chloride, 2-Chloro-6-Ethyl- (7Ci)
CAS No.	89938-71-6
Molecular Formula	C8H7Cl2NO
Molecular Weight	204.05 g/mol
Synonyms	2-Chloro-6-ethylisonicotinoyl chloride; 2-Chloro-6-ethylpyridine-4-carbonyl chloride; 4-Pyridinecarbonyl chloride, 2-chloro-6-ethyl-; 2-Chloro-6-ethyl-4-pyridinecarboxylic acid chloride; 2-Chloro-6-ethylisonicotinic acid chloride; 6-Ethyl-2-chloroisonicotinoyl chloride
EINECS	Contact for details

Quality Control

Every batch of Isonicotinoyl Chloride, 2-Chloro-6-Ethyl- (7Ci) is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical development, ensuring traceability and documentation excellence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.