Description

(3Ar)-2,3,3Aβ,4,5,7,9Aβ,9Bα-Octahydro-6,9-Dimethyl-3-Methylene-2-Oxoazuleno[4,5-B]Furan-4α-Ol (Z)-2-(Hydroxymethyl)-2-Butenoate is a complex, high-purity sesquiterpene lactone derivative with significant potential in advanced organic synthesis and pharmaceutical research. This compound is valued for its intricate azulene-fused furan structure, which serves as a critical scaffold for developing novel bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential therapeutic agents, particularly in anti-inflammatory and anticancer research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Advanced Organic Synthesis: Employed in complex multi-step syntheses to construct novel natural product analogs and complex molecular architectures.
• Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in research and development laboratories.
• Biochemical Research: Investigated for its interaction with biological targets and enzymes due to its unique fused-ring system.

Basic Information

Product Name	(3Ar)-2,3,3Aβ,4,5,7,9Aβ,9Bα-Octahydro-6,9-Dimethyl-3-Methylene-2-Oxoazuleno[4,5-B]Furan-4α-Ol (Z)-2-(Hydroxymethyl)-2-Butenoate
CAS No.	89900-51-6
Molecular Formula	C20H26O5
Molecular Weight	346.42 g/mol
Synonyms	Alantolactone Cinnamate; (Z)-Alantolactone Cinnamate; Isoalantolactone Cinnamate; (3aR,4S,9aR,9bS)-4-Hydroxy-6,9-dimethyl-3-methylidene-2-oxo-3a,4,5,7,9a,9b-hexahydroazuleno[4,5-b]furan-3a-yl (Z)-3-(hydroxymethyl)but-2-enoate; 89900-51-6; Alantolactone (Z)-2-(Hydroxymethyl)-2-butenoate
EINECS	Contact for details

Quality Control

Our (3Ar)-2,3,3Aβ,4,5,7,9Aβ,9Bα-Octahydro-6,9-Dimethyl-3-Methylene-2-Oxoazuleno[4,5-B]Furan-4α-Ol (Z)-2-(Hydroxymethyl)-2-Butenoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee compliance with research-grade standards and support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.