Description

Mpeg3-Propyne CAS NO 89635-82-5 is a specialized functionalized polyethylene glycol derivative, featuring a terminal alkyne group. This unique bifunctional structure makes it a critical intermediate for click chemistry, particularly in the synthesis of bioconjugates and advanced polymer materials. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and materials science sectors who require precise, high-purity linkers for drug delivery systems, diagnostic probes, and functional hydrogels.

Application

• Bioconjugation & Click Chemistry: Serves as a key linker for the site-specific attachment of drugs, peptides, or fluorescent dyes to antibodies, proteins, or nanoparticles via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Pharmaceutical Development: Used in the synthesis of antibody-drug conjugates (ADCs) and PEGylated therapeutics to enhance solubility, stability, and pharmacokinetic profiles.
• Polymer & Material Science: Acts as a functional monomer or cross-linker for creating smart polymers, hydrogels, and surface coatings with tailored properties.
• Diagnostic Reagents: Employed in the development of diagnostic assays and imaging probes where a stable, hydrophilic spacer is required.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic pathways in organic and medicinal chemistry.

Basic Information

Product Name	Mpeg3-Propyne
CAS No.	89635-82-5
Molecular Formula	C11H20O4
Molecular Weight	216.27 g/mol
Synonyms	3-(2-(2-(2-Methoxyethoxy)ethoxy)ethoxy)prop-1-yne; Propargyl-PEG3-methyl ether; mPEG3-Alkyne; Alkyne-PEG3-OMe; 2,5,8,11-Tetraoxatetradec-13-yn-14-yl methyl ether; Methyl-PEG3-propargyl ether; Propargyloxy tri(ethylene glycol) methyl ether; PEG3 methyl ether propargyl
EINECS	Contact for details

Quality Control

Our Mpeg3-Propyne is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.