Description

Piperazine-2,5-Dicarboxylic Acid is a high-purity, multifunctional organic building block of significant importance in advanced chemical synthesis. This compound serves as a key chiral intermediate and a versatile precursor for the development of complex molecules, particularly in the pharmaceutical sector. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, catalyst development, and material science.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors, kinase inhibitors, and other biologically active compounds.
• Ligand Synthesis: Used to prepare sophisticated chelating ligands for catalysis and metal-organic frameworks (MOFs), enabling applications in asymmetric synthesis and material design.
• Peptidomimetics & Conformationally Restricted Peptides: The piperazine dicarboxylic acid scaffold is integral for constructing peptidomimetics and cyclic peptides to enhance metabolic stability and receptor selectivity.
• Agrochemical Research: Employed as a precursor in the development of novel herbicides, fungicides, and plant growth regulators with specific chiral properties.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating functional polymers with specific chelating or hydrophilic properties.
• Chemical Research & Development: Serves as a versatile starting material in academic and industrial R&D for exploring new synthetic methodologies and novel chemical entities.

Basic Information

Product Name	Piperazine-2,5-Dicarboxylic Acid
CAS No.	89601-10-5
Molecular Formula	C6H8N2O4
Molecular Weight	172.14 g/mol
Synonyms	2,5-Piperazinedicarboxylic Acid; (2S,5S)-Piperazine-2,5-dicarboxylic Acid; (S,S)-Piperazine-2,5-dicarboxylic Acid; L,L-Piperazine-2,5-dicarboxylic Acid; NSC 163082; 1,4-Diazinane-2,5-dicarboxylic Acid; 2,5-Dicarboxypiperazine
EINECS	Contact for details

Quality Control

Our Piperazine-2,5-Dicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced research applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.