Description

Pyran-2-Carboxaldehyde, Tetrahydro-5,6-Dihydroxy- (7Ci) is a functionalized tetrahydropyran derivative, serving as a versatile chiral building block and synthetic intermediate. Its value lies in the presence of multiple reactive sites, including the aldehyde and diol functionalities, enabling its use in complex organic synthesis and pharmaceutical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those with complex sugar-like or polyol motifs.
• Asymmetric Synthesis: Utilized as a starting material or chiral auxiliary in stereoselective reactions to introduce specific stereocenters into target molecules.
• Natural Product Synthesis: Serves as a core building block in the total synthesis of natural products containing tetrahydropyran rings, such as certain macrolides and polyether antibiotics.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, or plant growth regulators that require specific chiral environments for activity.
• Ligand and Catalyst Development: The diol moiety can be used to create chelating ligands for metal catalysts used in homogeneous catalysis.
• Fine Chemical Production: Acts as a precursor for specialty chemicals, flavors, and fragrances requiring high-purity, defined stereochemistry intermediates.

Basic Information

Product Name	Pyran-2-Carboxaldehyde, Tetrahydro-5,6-Dihydroxy- (7Ci)
CAS No.	89489-81-6
Molecular Formula	C6H10O4
Molecular Weight	146.14 g/mol
Synonyms	5,6-Dihydroxytetrahydropyran-2-carboxaldehyde; (5R,6R)-5,6-Dihydroxy-3,4,5,6-tetrahydro-2H-pyran-2-carbaldehyde; Tetrahydro-5,6-dihydroxy-2-pyrancarboxaldehyde; 2-Formyl-5,6-dihydroxytetrahydropyran; (2R,3R)-2,3-Dihydroxy-6-oxooxane-4-carbaldehyde; Dihydroxy-tetrahydropyran carboxaldehyde; 89489-81-6 (CAS)
EINECS	Contact for details

Quality Control

Our Pyran-2-Carboxaldehyde, Tetrahydro-5,6-Dihydroxy- (7Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.