Description

Dansylhydrazide-Leucyl-Glycine is a specialized synthetic peptide derivative, primarily utilized as a high-purity biochemical reagent. Its core value lies in its role as a key intermediate and research tool in advanced proteomics and peptide synthesis, offering precise structural control. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent sectors who require custom peptide sequences for drug discovery, biomarker development, and analytical method validation.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel peptide-based drug candidates and targeted therapeutics.
• Proteomics & Biomarker Studies: Used as a derivatization agent or reference standard in mass spectrometry and HPLC-based protein/peptide analysis.
• Fluorescent Labeling & Detection: The dansyl moiety provides a fluorescent tag for tracking and quantifying peptides in complex biological matrices.
• Enzyme Substrate & Inhibitor Design: Acts as a building block for creating specific substrates or inhibitors to study protease and peptidase activity.
• Diagnostic Reagent Manufacturing: Incorporated into the development of high-sensitivity diagnostic assays and kits.
• Academic & Institutional Research: Employed in biochemical laboratories for studying peptide structure, function, and interactions.

Basic Information

Product Name	Dansylhydrazide-Leucyl-Glycine
CAS No.	89315-19-5
Molecular Formula	C23H34N6O5S
Molecular Weight	506.62 g/mol
Synonyms	5-(Dimethylamino)naphthalene-1-sulfonylhydrazide-L-leucylglycine; Dansyl-L-leucylglycine hydrazide; Dns-Leu-Gly-NHNH2; Nα-Dansyl-L-leucylglycine hydrazide; L-Leucyl-glycine, N-[5-(dimethylamino)-1-naphthalenesulfonyl]hydrazide; Dansyl hydrazide derivative of Leu-Gly dipeptide
EINECS	Contact for details

Quality Control

Our Dansylhydrazide-Leucyl-Glycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and easily oxidized nature. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.