Description

3-Chloro-5-Methylpyrazin-2(1H)-One is a high-purity heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a versatile intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development teams for the synthesis of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for the synthesis of functionalized heterocyclic compounds used in organic electronics and ligand design.
• Chemical Biology: Employed in the creation of molecular probes and biochemical tools for target identification and validation studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific pyrazinone scaffolds.

Basic Information

Product Name	3-Chloro-5-Methylpyrazin-2(1H)-One
CAS No.	89283-33-0
Molecular Formula	C5H5ClN2O
Molecular Weight	144.56 g/mol
Synonyms	3-Chloro-5-methyl-1H-pyrazin-2-one; 3-Chloro-5-methylpyrazin-2(1H)-one; 5-Methyl-3-chloro-2(1H)-pyrazinone; 2(1H)-Pyrazinone, 3-chloro-5-methyl-; 3-Chloro-5-methyl-2-hydroxypyrazine; 3-Chloro-5-methyl-1,2-dihydropyrazin-2-one
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Methylpyrazin-2(1H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.