Description

Ursodeoxycholate-3-Sulfate is a sulfated derivative of the primary bile acid ursodeoxycholic acid (UDCA). This chemical modification enhances its polarity and alters its biological activity, making it a valuable intermediate for advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for investigating bile acid metabolism and developing novel therapeutic agents. The compound is supplied with a high level of purity to meet the stringent requirements of these applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting liver and metabolic disorders.
• Biochemical Research: Used as a reference standard or probe in studies of bile acid transporters, nuclear receptors (e.g., FXR, TGR5), and cholestatic disease mechanisms.
• Metabolite Standard: Serves as an analytical standard in LC-MS or HPLC methods for the quantification of sulfated bile acid metabolites in biological samples.
• Prodrug Development: Investigated for the design of prodrugs with improved solubility or targeted delivery profiles.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to study the effects of sulfated bile acids on cell signaling and function.

Basic Information

Product Name	Ursodeoxycholate-3-Sulfate
CAS No.	89232-83-7
Molecular Formula	C24H40O7S
Molecular Weight	472.63 g/mol
Synonyms	Ursodeoxycholic Acid 3-Sulfate; 3-Sulfooxyursodeoxycholic Acid; 3α,7β-Dihydroxy-5β-cholan-24-oic Acid 3-Sulfate; UDCA 3-Sulfate; Ursodiol 3-Sulfate; 3-Sulfate Ester of Ursodeoxycholic Acid; (3α,5β,7β)-3,7-Dihydroxycholan-24-oic Acid 3-(Hydrogen Sulfate)
EINECS	Contact for details

Quality Control

Our Ursodeoxycholate-3-Sulfate is manufactured under a quality management system and undergoes rigorous analytical testing. Each batch is characterized by advanced techniques including HPLC, NMR, and MS to confirm identity and ensure high purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.