Description

Efaroxan Hydrochloride is a selective α-2 adrenergic receptor antagonist of significant interest in pharmacological research and development. This compound matters as a critical tool for studying autonomic nervous system regulation, cardiovascular function, and central nervous system pathways. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and contract research organizations (CROs) focused on neuropharmacology and cardiovascular diseases.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating α-2 adrenoceptor mechanisms.
• Neuropharmacology Studies: Employed in preclinical research to explore its effects on neurotransmitter release and central nervous system activity.
• Cardiovascular Research: Applied in experimental models to study blood pressure regulation, vascular tone, and heart rate control mediated by α-2 receptors.
• Biochemical Assay Development: Serves as a key ligand in developing and validating receptor binding assays and functional cellular tests.
• Reference Standard: Used in analytical laboratories for method development, calibration, and quality control of related pharmaceutical compounds.
• Drug Discovery Programs: Acts as a chemical starting point or a comparative compound in the discovery of new therapeutic agents targeting adrenergic pathways.

Basic Information

Product Name	Efaroxan Hydrochloride
CAS No.	89197-00-2
Molecular Formula	C13H16N2O • HCl
Molecular Weight	252.74 g/mol
Synonyms	Efaroxan HCl; 2-(2-Ethyl-2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole Hydrochloride; 2-(2-Ethyl-2,3-dihydro-1,4-benzodioxin-2-yl)-2-imidazoline Hydrochloride; Efaroxan Hydrochloride Salt; Idazoxan Analog; RX 821002 Hydrochloride (related compound); Benzodioxanyl Imidazoline Hydrochloride
EINECS	Contact for details

Quality Control

Our Efaroxan Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR, and tests for residual solvents and heavy metals to ensure it meets high-purity standards suitable for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with the agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.