Description

Insulin Los Angeles CAS NO 89147-46-6 is a high-purity synthetic peptide analog of insulin, specifically engineered for research and development applications. This compound is critical for advancing studies in diabetes research, metabolic disorders, and the development of novel therapeutic agents. It is an essential material for pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on endocrinology and peptide chemistry.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the development of novel insulin analogs and diabetes treatments.
• Biochemical Assay Development: Used as a critical reagent in the development and validation of immunoassays, receptor binding studies, and other analytical methods for insulin detection.
• Metabolic Disorder Studies: Employed in in vitro and in vivo research models to investigate insulin signaling pathways, glucose metabolism, and related disorders.
• Quality Control & Analytical Standards: Functions as a certified reference material (CRM) for the quality control and potency testing of commercial insulin products in regulatory environments.
• Peptide Chemistry & Synthesis: Acts as a model compound for studying peptide stability, formulation, and advanced drug delivery systems.

Basic Information

Product Name	Insulin Los Angeles
CAS No.	89147-46-6
Molecular Formula	C257H383N65O77S6
Molecular Weight	5807.9 g/mol
Synonyms	Insulin B Chain (B25 Phe → Leu); [LeuB25]-Insulin; Human Insulin (B25 Phe/Leu); Insulin, Leu-B25; Insulin Los Angeles Variant; [LeuB25]Human Insulin; Insulin (PheB25→Leu); 5-L-Leucineinsulin
EINECS	Contact for details

Quality Control

Our Insulin Los Angeles is manufactured under strict quality management systems. Each batch is subjected to a comprehensive suite of analytical tests, including HPLC for purity, peptide mapping for identity confirmation, and bioactivity assays. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Peptide Content (UV)	≥ 80.0%
Water Content (KF)	≤ 10.0%
Biological Potency	90% - 110% of stated potency
Sterility (for sterile grade)	Sterile / Contact for details
Endotoxin (for parenteral grade)	< 10 EU/mg / Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.