Description

(+/-)-15-Hydroxy-5Z,8Z,11Z,13E,17Z-Eicosapentaenoic Acid CAS NO 88852-33-9 is a specialized hydroxy fatty acid derivative of eicosapentaenoic acid (EPA), a key ω-3 fatty acid. This compound serves as a crucial biochemical intermediate and reference standard in lipidomics and inflammation research. It is primarily utilized by pharmaceutical R&D teams, analytical laboratories, and manufacturers of high-purity biochemicals for developing novel therapeutics and diagnostic assays.

Application

• Biochemical Research Standard: Used as a high-purity reference material in lipidomics, metabolomics, and eicosanoid pathway studies.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of novel anti-inflammatory and pro-resolving lipid mediators.
• Cell Signaling Studies: Employed in vitro and in vivo to investigate the role of specialized pro-resolving mediators (SPMs) in the resolution phase of inflammation.
• Analytical Chemistry: Acts as a critical calibration standard for HPLC, LC-MS, and GC-MS methods quantifying hydroxy fatty acids and their metabolites in biological samples.
• Nutritional Science Research: Used to study the metabolic fate and bioactive derivatives of dietary ω-3 fatty acids.
• Cosmeceutical R&D: Investigated for potential applications in topical formulations targeting inflammatory skin conditions due to its derived mediator activity.

Basic Information

Product Name	(+/-)-15-Hydroxy-5Z,8Z,11Z,13E,17Z-Eicosapentaenoic Acid
CAS No.	88852-33-9
Molecular Formula	C₂₀H₃₀O₃
Molecular Weight	318.45 g/mol
Synonyms	15-HEPE; 15-Hydroxy-5Z,8Z,11Z,13E,17Z-eicosapentaenoic acid; 15(S)-HETE (Note: This is a common but incorrect synonym for the EPA derivative; correct is 15-HEPE); 15-Hydroxyeicosapentaenoic acid; (±)-15-HEPE; 15-HETE (misnomer); 15-Hydroxy-EPA; 15-Hydroxyicosa-5Z,8Z,11Z,13E,17Z-pentaenoic acid
EINECS	Contact for details

Quality Control

Our production of (+/-)-15-Hydroxy-5Z,8Z,11Z,13E,17Z-Eicosapentaenoic Acid adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to ensure structural identity and purity. Certificates of Analysis (COA) detailing batch-specific purity, chromatographic data, and spectroscopic confirmation are provided to guarantee traceability and consistency for your critical research.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay (HPLC)	≥ 90% (by weight)
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.