Description

1,3-Dioxolane-4,5-Dicarbonyl Dichloride, (4R-Trans)- (9Ci) is a high-purity, chiral building block of significant interest in advanced organic synthesis. Its value lies in its role as a reactive intermediate for constructing complex, stereochemically defined molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and specialty agrochemicals where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, especially those requiring a specific (4R)-trans configuration.
• Agrochemical Synthesis: Used in the development of advanced, stereoselective pesticides and herbicides.
• Ligand and Catalyst Preparation: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Chemistry: Can be utilized in the synthesis of specialized, functional polymers with tailored properties.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry research.

Basic Information

Item	Details
Product Name	1,3-Dioxolane-4,5-Dicarbonyl Dichloride, (4R-Trans)- (9Ci)
CAS No.	88797-33-5
Molecular Formula	C5H4Cl2O4
Molecular Weight	198.99 g/mol
Synonyms	(4R,5R)-4,5-Bis(chlorocarbonyl)-1,3-dioxolane; (4R-trans)-1,3-Dioxolane-4,5-dicarbonyl dichloride; (4R,5R)-1,3-Dioxolane-4,5-dicarboxylic acid dichloride; (4R,5R)-4,5-Dicarboxy-1,3-dioxolane dichloride; L-Tartaric Acid 1,3-Dioxolane-4,5-dicarbonyl Dichloride Derivative; (R,R)-1,3-Dioxolane-4,5-dicarbonyl Dichloride
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4,5-Dicarbonyl Dichloride, (4R-Trans)- (9Ci) is manufactured under strict quality control protocols to ensure high chemical and chiral purity. Each batch is analyzed using advanced techniques including HPLC, NMR, and chiral analysis to confirm identity, potency, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee consistency and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.