Description

Adynerigenin β-Neritrioside is a specialized cardiac glycoside derivative, a high-purity reference standard and intermediate of significant interest in pharmaceutical research and development. Its value lies in its role as a precise chemical entity for analytical method development, quality control, and pharmacological studies. This compound is primarily needed by research institutions, pharmaceutical companies, and contract manufacturing organizations (CMOs) engaged in cardiovascular drug discovery, phytochemical analysis, and the production of high-value active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of related cardiac glycosides in drug substances and finished products.
• Biochemical Research: Serves as a key intermediate or substrate in studies investigating the mechanism of action, metabolism, and structure-activity relationships (SAR) of cardiotonic steroids.
• Natural Product Isolation & Standardization: Employed as a marker compound for the quality control and standardization of botanical extracts derived from plants in the Apocynaceae family, such as Nerium oleander.
• Analytical Method Development: Critical for developing and validating precise HPLC, LC-MS, and UPLC methods in quality control laboratories.
• Preclinical Studies: Utilized in in vitro and in vivo pharmacological research to explore potential therapeutic effects on heart function.
• Process Chemistry & Synthesis: Acts as a building block or intermediate in the semi-synthesis of novel derivatives for patentable new chemical entities (NCEs).

Basic Information

Item	Detail
Product Name	Adynerigenin β-Neritrioside
CAS No.	88721-09-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Adynerigenin β-Neritrioside; β-Neritrioside, Adynerigenin; 16-Acetylgitoxigenin β-neritrioside; Adynerigenin-β-D-neritrioside; Oleandrin metabolite reference standard; Cardiac glycoside intermediate; (3β,5β,11α,16β)-16-(Acetyloxy)-3,11,14-trihydroxycard-20(22)-enolide 3-[O-β-D-glucopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranoside]
EINECS	Contact for details

Quality Control

Our Adynerigenin β-Neritrioside is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment, ensuring full traceability and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.