Description

(3S)-3Aβ,4,5,6,6Aβ,7,8,9,9Aβ,9Bα-Decahydro-4β,8α,9β-Trihydroxy-9-(Hydroxymethyl)-3β-Methyl-6-Methyleneazuleno[4,5-B]Furan-2(3H)-One is a complex sesquiterpene lactone derivative with a unique azulene-fused furanone structure. This compound is of significant interest in advanced organic synthesis and pharmaceutical research due to its intricate molecular architecture and potential biological activity. It serves as a critical intermediate or reference standard for researchers in medicinal chemistry, process development, and natural product synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel drug candidates, particularly in anti-inflammatory and anti-cancer research.
• Medicinal Chemistry Research: Used as a reference standard or a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Natural Product Synthesis: Acts as a synthetic target or intermediate in the total synthesis of complex sesquiterpenoids and related natural products.
• Process Development: Employed in the development and scaling of stereoselective synthetic routes for complex organic molecules.
• Biochemical Research: Investigated for its potential interaction with biological targets and enzyme inhibition studies.
• Analytical Standard: Provides a high-purity standard for method development and quality control in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	(3S)-3Aβ,4,5,6,6Aβ,7,8,9,9Aβ,9Bα-Decahydro-4β,8α,9β-Trihydroxy-9-(Hydroxymethyl)-3β-Methyl-6-Methyleneazuleno[4,5-B]Furan-2(3H)-One
CAS No.	88664-02-2
Molecular Formula	C15H20O6
Molecular Weight	296.32 g/mol
Synonyms	6-Methyleneazuleno[4,5-b]furan-2(3H)-one, 3aβ,4,5,6,6aβ,7,8,9,9aβ,9bα-decahydro-4β,8α,9β-trihydroxy-9-(hydroxymethyl)-3β-methyl-, (3S)-; Parthenolide derivative; Sesquiterpene lactone analog; Azulenofuranone; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (3S)-3Aβ,4,5,6,6Aβ,7,8,9,9Aβ,9Bα-Decahydro-4β,8α,9β-Trihydroxy-9-(Hydroxymethyl)-3β-Methyl-6-Methyleneazuleno[4,5-B]Furan-2(3H)-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and structural confirmation via NMR and MS, to ensure identity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support custom synthesis to meet specific research-grade or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under inert atmosphere at -20°C to maintain stability. The compound may be hygroscopic and/or light-sensitive; handle and store accordingly.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.