Description

1-Stearoyl-2-Arachidonoyl Phosphatidylinositol is a high-purity, synthetic phospholipid with a defined fatty acid composition. This compound is a critical biochemical tool and intermediate for advanced research in cellular signaling and lipid metabolism. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and manufacturers of diagnostic reagents and lipid-based delivery systems.

Application

• Biochemical Research: A key substrate for studying the enzymatic activity of phospholipases, particularly Phospholipase C (PLC) and Phospholipase A2 (PLA2), in signal transduction pathways.
• Lipidomics & Metabolomics: Serves as a critical standard or reference compound for the identification and quantification of phosphatidylinositol species in mass spectrometry-based lipid analysis.
• Pharmaceutical Development: Used as a precursor or model compound in the development of drugs targeting phosphoinositide-specific pathways, which are implicated in cancer, inflammation, and neurological disorders.
• Cell Biology Studies: Employed in membrane biophysics research to investigate the role of specific phosphatidylinositols in membrane structure, curvature, and protein recruitment.
• Diagnostic Reagent Manufacturing: Incorporated into test kits and assays designed to measure enzyme activity or detect specific lipid biomarkers in clinical samples.
• Liposome & Drug Delivery System Formulation: Acts as a specialized component to create targeted liposomal carriers with specific membrane properties for drug delivery applications.

Basic Information

Product Name	1-Stearoyl-2-Arachidonoyl Phosphatidylinositol
CAS No.	88587-98-8
Molecular Formula	C53H95O13P
Molecular Weight	971.3 g/mol
Synonyms	PI(18:0/20:4); Phosphatidylinositol (18:0/20:4); 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-myo-inositol); SAPtdIns; 1-Octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1'-myo-inositol); (3S)-2,3-Dihydroxypropyl (1R)-2-(octadecanoyloxy)-3-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyloxy]propyl hydrogen phosphate
EINECS	Contact for details

Quality Control

Our 1-Stearoyl-2-Arachidonoyl Phosphatidylinositol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via mass spectrometry and NMR. Certificates of Analysis (COA) detailing batch-specific results are provided to ensure traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95% (Area %)
Assay (Phosphorus Content)	≥ 98%
Solubility	Soluble in chloroform, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.