Description

1-Hexadecyl-2-Palmitoyl-Sn-Glycero-3-Phosphocholine is a high-purity synthetic phospholipid, specifically a phosphatidylcholine derivative. This compound is a critical component for constructing biomimetic membranes and liposomal delivery systems, offering superior consistency and batch-to-batch reproducibility. It is essential for researchers and manufacturers in advanced pharmaceutical development, particularly for drug delivery, diagnostic imaging, and fundamental biophysical studies of membrane structure and function.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural lipid for creating stable, uniform liposomes used in drug delivery systems for vaccines, cancer therapeutics, and nucleic acid (e.g., mRNA) encapsulation.
• Biomembrane & Model Membrane Studies: Used to create defined lipid bilayers (e.g., supported lipid bilayers, vesicles) for studying membrane protein interactions, permeability, and cell signaling mechanisms.
• Diagnostic Agent Carrier: Serves as a component in contrast agents for medical imaging techniques such as ultrasound and MRI, where stable, targeted carriers are required.
• Cosmetic & Dermal Delivery Systems: Incorporated into advanced cosmetic formulations like niosomes and transfersomes for enhanced skin penetration and stabilization of active ingredients.
• Cell Culture & Biotechnology: Used as a supplement in serum-free media or for creating lipid coatings to improve cell growth and viability in specialized culture systems.
• Reference Standard & Analytical Chemistry: Employed as a high-purity standard in HPLC, MS, and other analytical methods for lipidomics research and quality control of phospholipid-based products.

Basic Information

Product Name	1-Hexadecyl-2-Palmitoyl-Sn-Glycero-3-Phosphocholine
CAS No.	88587-94-4
Molecular Formula	C40H82NO8P
Molecular Weight	736.06 g/mol
Synonyms	16:0-16:0 PC (Ether-Ester); 1-O-Hexadecyl-2-palmitoyl-sn-glycero-3-phosphocholine; DPPC Ether-Ester Analog; C16 Alkyl-C16 Acyl Phosphatidylcholine; Palmitoyl Alkyl Phosphatidylcholine; Phosphatidylcholine, 1-hexadecyl-2-palmitoyl-; Ether-Linked DPPC; Lyso Platelet-Activating Factor C-16 Analog
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and lipid composition. Certificates of Analysis (COA) are available upon request, providing detailed results for parameters such as assay (HPLC), residual solvents, and related substances. We support cGMP manufacturing for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR & NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (TLC)	Single spot
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.