Description

(5R,6R)-5,6-Dihydro-7-Methylbenz[A]Anthracene-5,6-Diol is a stereospecific dihydrodiol derivative of a methyl-substituted benz[a]anthracene, representing a key chiral intermediate in advanced organic synthesis. This compound matters for its role as a critical building block in the research and development of complex polycyclic aromatic hydrocarbon (PAH) metabolites and related bioactive molecules. It is primarily needed by pharmaceutical R&D laboratories, analytical reference standard producers, and academic institutions focused on carcinogenicity studies, metabolic pathway elucidation, and stereoselective synthesis.

Application

• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for quantifying metabolites in pharmacokinetic and toxicological studies.
• Metabolic Pathway Research: Used as a precise intermediate to study the enzymatic formation and further reactions of benz[a]anthracene dihydrodiols in biological systems.
• Organic Synthesis Building Block: Acts as a chiral precursor for the synthesis of more complex PAH derivatives, diolepoxides, and tetrols for structure-activity relationship (SAR) studies.
• Carcinogenicity & Mutagenicity Assays: Employed in controlled laboratory experiments to investigate the mechanisms of PAH-induced carcinogenesis.
• Chemical Biology Probes: Utilized in developing molecular probes to understand DNA adduct formation and repair mechanisms related to specific stereoisomers.

Basic Information

Product Name	(5R,6R)-5,6-Dihydro-7-Methylbenz[A]Anthracene-5,6-Diol
CAS No.	88244-39-7
Molecular Formula	C19H16O2
Molecular Weight	276.33 g/mol
Synonyms	(5R,6R)-7-Methylbenz[a]anthracene-5,6-dihydrodiol; (5R,6R)-7-Methylbenz[a]anthracene-5,6-diol; 7-Methylbenz[a]anthracene (5R,6R)-dihydrodiol; (5R,6R)-Dihydro-7-methylbenz[a]anthracene-5,6-diol; (5R,6R)-5,6-Dihydroxy-5,6-dihydro-7-methylbenz[a]anthracene; 7-MBA (5R,6R)-dihydrodiol; MBA-dihydrodiol (R,R-isomer)
EINECS	Contact for details

Quality Control

Our (5R,6R)-5,6-Dihydro-7-Methylbenz[A]Anthracene-5,6-Diol is produced under strict quality-controlled conditions to ensure batch-to-batch consistency and high stereochemical purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and identity confirmation. We adhere to rigorous internal standards suitable for research and development applications, ensuring reliable and traceable material for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light tan solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% (5R,6R)
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.