Description

Levistilide A is a bioactive natural product and a key phthalide compound isolated from traditional Chinese medicinal herbs. This compound is of significant commercial and research interest due to its potent biological activities, particularly in the areas of neuroprotection and cardiovascular health. It is primarily sought after by the pharmaceutical, nutraceutical, and advanced research sectors for use in drug discovery, high-purity reference standards, and the development of novel therapeutic formulations.

Application

• Pharmaceutical Intermediates & Drug Discovery: Serves as a critical lead compound and building block for synthesizing novel neuroprotective and cardioprotective agents.
• Reference Standards & Analytical Testing: Used as a high-purity certified reference material (CRM) for quality control and analytical method development in laboratories.
• Nutraceutical & Dietary Supplement Formulation: Incorporated into advanced supplements targeting cognitive function and circulatory health, leveraging its natural origin.
• Academic & Clinical Research: Essential for in vitro and in vivo studies investigating mechanisms of action related to ischemia-reperfusion injury, platelet aggregation, and neuronal apoptosis.
• Cosmeceutical Ingredients: Explored for topical formulations aimed at improving microcirculation and providing anti-inflammatory benefits for skin health.

Basic Information

Product Name	Levistilide A
CAS No.	88182-33-6
Molecular Formula	C24H28O4
Molecular Weight	380.48 g/mol
Synonyms	(3Z)-3-[(1S)-3,4-Dimethoxyphenyl]methylene]-6,7-dimethoxy-1(3H)-isobenzofuranone; (Z)-Levistilide A; Ligustilide derivative; Senkyunolide analogue; Phthalide dimer; 3-[(3,4-Dimethoxyphenyl)methylene]-6,7-dimethoxy-1(3H)-isobenzofuranone
EINECS	Contact for details

Quality Control

Our Levistilide A is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.