Description

2-o-Caffeoyl Arbutin is a high-purity, synthetically derived ester of arbutin and caffeic acid, representing a potent and stable active ingredient for advanced formulations. This compound is valued for its enhanced efficacy as a skin-brightening and antioxidant agent, offering superior stability and performance compared to its precursors. It is primarily sought by manufacturers in the cosmetic, personal care, and pharmaceutical industries for developing premium skincare products targeting hyperpigmentation and photoaging.

Application

• Skin-Brightening Cosmetics: A key active in serums, creams, and lotions designed to inhibit melanin production and reduce the appearance of dark spots and uneven skin tone.
• Anti-Aging Formulations: Incorporated into products for its potent antioxidant properties, helping to neutralize free radicals and protect skin from environmental stressors.
• Pharmaceutical Topicals: Used in the development of medicated creams and ointments for conditions related to hyperpigmentation, such as melasma.
• Premium Personal Care: Found in high-end cleansers, toners, and masks that aim to deliver clarifying and radiance-boosting benefits.
• Cosmeceutical R&D: Serves as a reference standard and active ingredient in research for novel dermal delivery systems and efficacy studies.
• Functional Additive: Potential use as a stabilizing or synergistic agent in formulations containing other light-sensitive or easily oxidized actives.

Basic Information

Item	Detail
Product Name	2-o-Caffeoyl Arbutin
CAS No.	14477-53-3
Molecular Formula	C21H22O11
Molecular Weight	450.39 g/mol
Synonyms	2-O-Caffeoylarbutin; Arbutin Caffeate; Caffeic Acid Arbutin Ester; 4-Hydroxyphenyl β-D-Glucopyranoside 2-(3,4-Dihydroxycinnamate); Kojic Acid Derivative (related compound); Skin Brightening Agent CA; p-Hydroxyphenyl-β-D-glucopyranoside caffeoyl ester
EINECS	Contact for details

Quality Control

Our 2-o-Caffeoyl Arbutin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of the cosmetic and pharmaceutical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen) for long-term stability and to minimize degradation. Keep away from excessive heat and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.