Description

D-(-)-Salicin CAS NO 138-52-3 is a naturally occurring phenolic glucoside and a key biochemical precursor to salicylic acid. This compound is valued for its role as a fundamental building block in pharmaceutical research and development. It is primarily sought after by manufacturers in the pharmaceutical, nutraceutical, and fine chemical synthesis industries for its anti-inflammatory properties and as a reference standard.

Application

• Pharmaceutical Intermediate: A critical starting material for the synthesis of salicylic acid derivatives and other analgesic/anti-inflammatory agents.
• Biochemical Research: Used as a standard or reagent in enzymatic studies, particularly those involving β-glucosidase activity.
• Nutraceutical Formulations: Incorporated into dietary supplements for its historical use as a natural pain reliever and anti-inflammatory compound.
• Reference Standard: Serves as a high-purity certified reference material (CRM) for quality control and analytical method development in laboratories.
• Fine Chemical Synthesis: Employed in organic synthesis to create more complex molecules for medicinal chemistry and material science.

Basic Information

Product Name	D-(-)-Salicin
CAS No.	138-52-3
Molecular Formula	C13H18O7
Molecular Weight	286.28 g/mol
Synonyms	Salicin; D-Salicin; (-)-Salicin; Salicoside; 2-(Hydroxymethyl)phenyl-β-D-glucopyranoside; Saligenin-β-D-glucopyranoside; Helicin (aglycone derivative); NSC 407098
EINECS	205-331-3

Quality Control

Our D-(-)-Salicin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial use. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Specific Rotation [α]²⁰D	-62° to -67° (c=3 in H₂O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.