Description

[(2R,3R,4S,5R,6R)-4,5-Dihydroxy-2-[(1R,2S)-2-Hydroxycyclohexyl]Oxy-6-(Hydroxymethyl)Oxan-3-Yl] 3-(4-Hydroxyphenyl)Prop-2-Enoate is a high-purity, complex glycosidic derivative of caffeic acid, valued for its specific stereochemistry and bioactive potential. This compound is critical for research and development in advanced pharmaceutical synthesis, particularly for creating novel therapeutic agents. It serves as a key chiral intermediate or reference standard for scientists in medicinal chemistry, pharmacology, and natural product development.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of novel drug candidates, particularly those targeting inflammation, metabolic disorders, or neurological conditions.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and NMR for method development, validation, and quality control of related compounds.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore the biological effects of specific glycosidic linkages and stereochemistry.
• Natural Product Synthesis: Acts as a synthetic target or intermediate in the total synthesis of complex natural products containing caffeic acid derivatives.
• Biochemical Research: Investigated for its potential enzyme inhibitory or receptor-binding activities in biochemical and pharmacological assays.
• Cosmeceutical R&D: Explored for potential antioxidant and skin-protective properties in advanced cosmetic and dermatological formulations.

Basic Information

Item	Details
Product Name	[(2R,3R,4S,5R,6R)-4,5-Dihydroxy-2-[(1R,2S)-2-Hydroxycyclohexyl]Oxy-6-(Hydroxymethyl)Oxan-3-Yl] 3-(4-Hydroxyphenyl)Prop-2-Enoate
CAS No.	15732-48-6
Molecular Formula	C22H28O9
Molecular Weight	436.45 g/mol
Synonyms	Caffeic Acid Glucoside Cyclohexyl Derivative; (1R,2S)-2-{[(2R,3R,4S,5R,6R)-3-[(E)-3-(4-Hydroxyphenyl)prop-2-enoyl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}cyclohexan-1-ol; Cyclohexyl Caffeoyl Glucoside; 4-Hydroxycinnamic Acid Glucoside Ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [(2R,3R,4S,5R,6R)-4,5-Dihydroxy-2-[(1R,2S)-2-Hydroxycyclohexyl]Oxy-6-(Hydroxymethyl)Oxan-3-Yl] 3-(4-Hydroxyphenyl)Prop-2-Enoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis to confirm stereochemical integrity, and spectroscopic identification (NMR, MS). Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee (by chiral HPLC)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.