Description

5,6-Dehydrokawain is a bioactive natural product belonging to the class of kavalactones, originally derived from the kava plant (Piper methysticum). This compound is of significant interest for its potential physiological effects and serves as a valuable reference standard and research chemical. It is primarily utilized by researchers and manufacturers in the pharmaceutical, nutraceutical, and life science sectors for analytical, development, and quality control purposes.

Application

• Pharmaceutical Research: Used as a reference standard in the analytical profiling and quality control of kava extracts and related botanical products.
• Bioactivity Studies: Serves as a key compound in pharmacological research to investigate potential anti-inflammatory, anxiolytic, or neuroprotective properties.
• Nutraceutical Development: Employed in the formulation and standardization of herbal supplements where kavalactone content is a critical quality marker.
• Analytical Chemistry: Acts as a high-purity calibrant for chromatographic methods (HPLC, GC) and spectroscopic analysis in laboratory settings.
• Chemical Synthesis: Functions as a building block or intermediate for the synthesis of novel analogs in medicinal chemistry programs.

Basic Information

Product Name	5,6-Dehydrokawain
CAS No.	1952-41-6
Molecular Formula	C₁₄H₁₂O₃
Molecular Weight	228.24 g/mol
Synonyms	5,6-Didehydrokawain; (E)-1-(6-(1,3-Benzodioxol-5-yl)-4-methoxy-2-oxo-2H-pyran-3(6H)-ylidene)propan-2-one; 5,6-Dehydrokavain; 5,6-DHK; NSC 407324; FEMA 3948; Kawain dehydro derivative
EINECS	217-810-9

Quality Control

Our 5,6-Dehydrokawain is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for identity confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.