Description

Leukotriene B3 is a bioactive lipid mediator belonging to the leukotriene family, specifically a metabolite of eicosatrienoic acid. This compound is of significant interest in biochemical and pharmacological research due to its role as a potent pro-inflammatory mediator involved in various immune and allergic responses. It is primarily utilized by researchers and pharmaceutical developers in the fields of immunology, inflammation studies, and drug discovery for investigating leukotriene pathways and developing targeted therapeutics.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of eicosanoid biosynthesis and metabolism.
• Pharmacological Studies: Critical for in vitro and in vivo research on inflammation, asthma, and allergic disease mechanisms.
• Drug Discovery & Development: Serves as a key biological target or tool compound for screening and validating new anti-inflammatory drugs.
• Cell Signaling Research: Employed to study receptor-ligand interactions and downstream signaling cascades involving BLT receptors.
• Academic & Institutional Laboratories: Essential for fundamental research in universities and research institutes focusing on lipid mediators.

Basic Information

Product Name	Leukotriene B3
CAS No.	88099-35-8
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.5 g/mol
Synonyms	LTB3; (5S,12R)-Dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic Acid; 5(S),12(R)-Dihydroxy-6,8,10,14-eicosatetraenoic Acid; (5S,12R)-Dihydroxyicosa-6Z,8E,10E,14Z-tetraenoic Acid; Leukotriene B-3; 5,12-DiHETE
EINECS	Contact for details

Quality Control

Our Leukotriene B3 is produced and handled under strict quality protocols suitable for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Solubility	Soluble in ethanol, DMSO; sparingly soluble in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.