Description

[R,(+)]-1-O,2-o-Dipalmitoyl-L-Glycerol 3-(Phosphoric Acid Dimethyl) Ester is a high-purity, enantiomerically defined phospholipid derivative, specifically a phosphatidic acid analog. This compound is a critical advanced intermediate for synthesizing complex phospholipids and lipid conjugates used in cutting-edge research and pharmaceutical development. It is essential for scientists and manufacturers in lipidomics, drug delivery systems (liposomes), and membrane biophysics who require structurally precise building blocks.

Application

• Pharmaceutical Research & Development: As a key chiral intermediate for the synthesis of novel phospholipid-based active pharmaceutical ingredients (APIs) and prodrugs.
• Advanced Drug Delivery: A precursor for constructing functionalized liposomal and nanoparticle carriers for targeted drug and gene delivery applications.
• Biochemical Research: Used in studies of lipid metabolism, enzyme kinetics (e.g., phospholipase assays), and as a standard in lipidomic analysis.
• Membrane Science: Employed to create model membrane systems for investigating protein-lipid interactions and membrane dynamics.
• Diagnostic Reagents: Serves as a starting material for synthesizing specialized lipids used in diagnostic kits and biosensors.

Basic Information

Product Name	[R,(+)]-1-O,2-o-Dipalmitoyl-L-Glycerol 3-(Phosphoric Acid Dimethyl) Ester
CAS No.	88082-31-9
Molecular Formula	C39H77O8P
Molecular Weight	705.00 g/mol
Synonyms	1,2-Dipalmitoyl-sn-glycerol-3-phosphate dimethyl ester; (R)-1,2-Dihexadecanoyl-3-(dimethyl phosphate)-sn-glycerol; DPPA dimethyl ester; 1,2-Dipalmitoylphosphatidic acid dimethyl ester; sn-Glycerol-3-phosphate dimethyl ester, 1,2-dipalmitoyl; L-α-Phosphatidic acid dimethyl ester, dipalmitoyl; PA(DMP) dimethyl ester; 1,2-Di-O-palmitoyl-3-O-(dimethylphosphoryl)-sn-glycerol
EINECS	Contact for details

Quality Control

Every batch of this specialty phospholipid is produced under strict quality control protocols. We ensure identity, purity, and enantiomeric excess through advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and potentially oxidizable nature. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, desiccants are recommended.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.