Description

Pyruvic Acid, Sodium Salt (1-13C) is a stable, isotopically labeled sodium salt of pyruvic acid, where the carbon-13 isotope is incorporated at the C-1 position. This compound is essential for advanced research and development, providing a critical tool for metabolic pathway tracing and nuclear magnetic resonance (NMR) spectroscopy studies. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in drug discovery, metabolic engineering, and diagnostic agent development.

Application

• Metabolic Flux Analysis (MFA): Used as a 13C-labeled tracer to study central carbon metabolism in cells, including glycolysis and the TCA cycle.
• NMR Spectroscopy: Serves as a standard or substrate in 13C-NMR experiments for structural elucidation and quantitative analysis of biochemical processes.
• Drug Metabolism & Pharmacokinetics (DMPK): Employed in isotope-labeled studies to track the metabolic fate of new chemical entities and understand drug disposition.
• Biochemical Research: Acts as a key intermediate in enzymatic studies and in vitro assays investigating pyruvate dehydrogenase and related enzymes.
• Diagnostic Agent Development: Potential use in the synthesis of advanced contrast agents or probes for molecular imaging techniques like hyperpolarized 13C-MRI.
• Stable Isotope Labeling: A fundamental building block for the synthesis of more complex 13C-labeled compounds for research purposes.

Basic Information

Product Name	Pyruvic Acid, Sodium Salt (1-13C)
CAS No.	87976-71-4
Molecular Formula	C3H313COONa
Molecular Weight	112.05 g/mol (for 13C1 isotopologue)
Synonyms	Sodium Pyruvate-1-13C; (1-13C)Pyruvic Acid Sodium Salt; Sodium 2-oxopropanoate-1-13C; 1-13C-Labeled Sodium Pyruvate; Pyruvic-1-13C Acid Sodium Salt; 2-Oxopropanoic-1-13C Acid Sodium Salt; Na Pyruvate-1-13C
EINECS	Contact for details

Quality Control

Our Pyruvic Acid, Sodium Salt (1-13C) is manufactured under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements of research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >99 atom % 13C), chemical purity, and identity confirmation via spectroscopic methods. We adhere to rigorous internal quality standards to guarantee batch-to-batch consistency and reliability for your critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment	≥99 atom % 13C
Assay (HPLC)	≥98.0% (anhydrous basis)
Water Content (KF)	≤2.0%
pH (5% solution)	6.0 - 8.0
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.