Description

5-[4-(Trifluoromethyl)Phenyl]-2-Piperidone is a high-value, fluorinated piperidone derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethylphenyl group, makes it an essential intermediate for developing novel pharmaceuticals and agrochemicals with enhanced metabolic stability and bioavailability. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of central nervous system (CNS) active drugs, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new chemical reactions, catalytic processes, and structure-activity relationships (SAR).
• Fluorine Chemistry Building Block: Essential for introducing the trifluoromethylphenyl moiety into complex molecules, a common strategy in modern medicinal and agrochemistry.

Basic Information

Product Name	5-[4-(Trifluoromethyl)Phenyl]-2-Piperidone
CAS No.	87922-74-5
Molecular Formula	C12H12F3NO
Molecular Weight	243.23 g/mol
Synonyms	5-[4-(Trifluoromethyl)phenyl]piperidin-2-one; 2-Piperidinone, 5-[4-(trifluoromethyl)phenyl]-; 5-(4-Trifluoromethylphenyl)-2-piperidone; 5-(α,α,α-Trifluoro-p-tolyl)-2-piperidone; 87922-74-5; 5-(4-Trifluoromethylphenyl)piperidin-2-one
EINECS	Contact for details

Quality Control

Our production of 5-[4-(Trifluoromethyl)Phenyl]-2-Piperidone adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and manufacturing standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.