Description

2-Chloro-5-Nitropyrazine is a versatile heterocyclic building block characterized by its reactive chloro and nitro substituents. This compound is essential for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to introduce pyrazine-based scaffolds into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging the pyrazine core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands in coordination chemistry and catalysts for organic transformations.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs).
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing specialized dyes and pigments due to its nitro-aromatic structure.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom chemical synthesis services catering to R&D and scale-up projects.

Basic Information

Product Name	2-Chloro-5-Nitropyrazine
CAS No.	87885-45-8
Molecular Formula	C4H2ClN3O2
Molecular Weight	159.53 g/mol
Synonyms	5-Nitro-2-chloropyrazine; 2-Chloro-5-nitropyrazine; 2-Chloro-5-nitro-1,4-diazine; Pyrazine, 2-chloro-5-nitro-; 2-Chlor-5-nitropyrazin (German); 2-クロロ-5-ニトロピラジン (Japanese); 2-氯-5-硝基吡嗪 (Chinese)
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Nitropyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.