Description

Piperazine, 1-(1,4-Benzodioxin-6-Ylmethyl)-4-(2-Pyrimidinyl)-, Dihydro Chloride is a high-purity, specialized piperazine derivative with significant potential in advanced pharmaceutical research and development. This compound matters as a critical building block for medicinal chemists seeking to develop novel therapeutic agents, particularly within the central nervous system (CNS) and cardiovascular domains. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-quality intermediate to support the synthesis of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel drug candidates, particularly for CNS-targeting therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step synthesis of complex target molecules for preclinical and clinical evaluation.
• Biochemical Tool Compound: Potential utility as a research-grade ligand or inhibitor for probing specific biological pathways in academic and industrial settings.
• Fine Chemical Production: Integrated into custom synthesis projects for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	Piperazine, 1-(1,4-Benzodioxin-6-Ylmethyl)-4-(2-Pyrimidinyl)-, Dihydro Chloride
CAS No.	87787-57-3
Molecular Formula	C₁₇H₂₀Cl₂N₄O₂
Molecular Weight	383.27 g/mol
Synonyms	1-[(2,3-Dihydro-1,4-benzodioxin-6-yl)methyl]-4-(pyrimidin-2-yl)piperazine dihydrochloride; 1-(1,4-Benzodioxan-6-ylmethyl)-4-pyrimidin-2-ylpiperazine dihydrochloride; 6-({4-(Pyrimidin-2-yl)piperazin-1-yl}methyl)-2,3-dihydro-1,4-benzodioxine dihydrochloride; 1,4-Benzodioxin-6-ylmethyl-4-(2-pyrimidinyl)piperazine dihydrochloride; 87787-57-3; UNII-9K7Q4WY8JN; 9K7Q4WY8JN
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(1,4-Benzodioxin-6-Ylmethyl)-4-(2-Pyrimidinyl)-, Dihydro Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and regulatory compliance ensures a reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.