Description

1-Piperazineethanol, 4-(Diphenylmethyl)-α-(4-Hydroxyphenyl)-, Mono Hydrochloride is a high-purity, complex organic compound primarily utilized as a key pharmaceutical intermediate. Its value lies in its specific molecular architecture, which is critical for synthesizing advanced active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This product is essential for research and development chemists, process scale-up teams, and manufacturers in the pharmaceutical and fine chemical industries seeking reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug research.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step synthetic routes to construct complex molecular frameworks for final drug substances.
• Biochemical Research: Serves as a reference standard or a starting material for investigating structure-activity relationships (SAR) in medicinal chemistry.
• Process Development & Scale-up: Employed in optimizing synthetic pathways from laboratory to pilot plant and commercial manufacturing scales.
• Fine Chemical Production: Utilized in the manufacture of specialized, high-value chemicals requiring precise molecular control.

Basic Information

Item	Details
Product Name	1-Piperazineethanol, 4-(Diphenylmethyl)-α-(4-Hydroxyphenyl)-, Mono Hydrochloride
CAS No.	87429-91-2
Molecular Formula	C25H28N2O2 • HCl
Molecular Weight	424.97 g/mol
Synonyms	4-(Diphenylmethyl)-α-(4-hydroxyphenyl)-1-piperazineethanol hydrochloride; 1-Piperazineethanol, 4-(benzhydryl)-α-(4-hydroxyphenyl)-, monohydrochloride; 4-(Benzhydryl)-α-(4-hydroxyphenyl)-1-piperazineethanol hydrochloride; α-(4-Hydroxyphenyl)-4-(diphenylmethyl)-1-piperazineethanol hydrochloride; (R*,S*)-α-(4-Hydroxyphenyl)-4-(diphenylmethyl)-1-piperazineethanol monohydrochloride; 87429-91-2 (CAS); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of 1-Piperazineethanol, 4-(Diphenylmethyl)-α-(4-Hydroxyphenyl)-, Mono Hydrochloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes results from advanced techniques like HPLC, NMR, and mass spectrometry. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, ensuring traceability and reliability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.