Description

1-(3-Chloropyridin-4-Yl)Piperazine is a versatile and high-value heterocyclic building block, crucial for the synthesis of complex organic molecules. Its core value lies in its dual functionality, combining a chloropyridine moiety with a piperazine ring, making it an essential intermediate for medicinal chemistry and advanced material science. This compound is primarily needed by research institutions and pharmaceutical companies engaged in developing new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the chloropyridine structure imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating complex ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new heterocyclic chemistry and reaction pathways.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	1-(3-Chloropyridin-4-Yl)Piperazine
CAS No.	87394-66-9
Molecular Formula	C9H12ClN3
Molecular Weight	197.66 g/mol
Synonyms	1-(3-Chloro-4-pyridinyl)piperazine; 4-(Piperazin-1-yl)-3-chloropyridine; 3-Chloro-4-(piperazin-1-yl)pyridine; 3-Chloro-4-piperazin-1-ylpyridine; 1-(3-Chloro-4-pyridyl)piperazine; 87394-66-9; 3-Chloro-4-(1-piperazinyl)pyridine
EINECS	Contact for details

Quality Control

Our 1-(3-Chloropyridin-4-Yl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.