Description

1-(5-Chloro-Pyridin-2-Yl)-Piperazine is a high-purity, versatile heterocyclic building block and key pharmaceutical intermediate. This compound is essential for the synthesis of complex molecules, offering a critical point of functionalization for medicinal chemistry and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal complexation.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	1-(5-Chloro-Pyridin-2-Yl)-Piperazine
CAS No.	87394-65-8
Molecular Formula	C9H12ClN3
Molecular Weight	197.66 g/mol
Synonyms	1-(5-Chloropyridin-2-yl)piperazine; 2-(1-Piperazinyl)-5-chloropyridine; 5-Chloro-2-piperazin-1-ylpyridine; 5-Chloro-2-(piperazin-1-yl)pyridine; 5-Chloro-2-piperazinylpyridine; 1-(5-Chloro-2-pyridinyl)piperazine; 87394-65-8; 5-Chloro-2-(1-piperazinyl)pyridine
EINECS	Contact for details

Quality Control

Our 1-(5-Chloro-Pyridin-2-Yl)-Piperazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.