Description

1-Piperazineethanol, 4-(2-(3,4-Dimethoxyphenyl)-1-(4-Methylphenyl)Ethy L)-, Dihydrochloride is a high-purity, complex organic salt with significant pharmacological research interest. This compound matters for its role as a key intermediate in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular pathways. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for developing new therapeutic agents and process optimization.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and cardiovascular research.
• Biochemical Research: Used as a reference standard or reagent in studies investigating receptor binding and enzyme inhibition.
• Process Chemistry Development: Serves as a key starting material (KSM) or advanced intermediate for scaling up API manufacturing processes under GMP conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and pre-clinical development of new chemical entities.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry projects and pharmacological studies.

Basic Information

Product Name	1-Piperazineethanol, 4-(2-(3,4-Dimethoxyphenyl)-1-(4-Methylphenyl)Ethy L)-, Dihydrochloride
CAS No.	87203-81-4
Molecular Formula	C21H28N2O3 · 2HCl
Molecular Weight	437.38 g/mol (free base: 356.46 g/mol)
Synonyms	4-[2-(3,4-Dimethoxyphenyl)-1-(4-methylphenyl)ethyl]-1-piperazineethanol dihydrochloride; 1-Piperazineethanol, 4-[2-(3,4-dimethoxyphenyl)-1-(4-methylphenyl)ethyl]-, dihydrochloride; 87203-81-4; 4-(2-(3,4-Dimethoxyphenyl)-1-phenylethyl)-1-piperazineethanol dihydrochloride (related); Dimethoxyphenyl-methylphenylethyl piperazineethanol dihydrochloride; Research compound 87203-81-4.
EINECS	Contact for details

Quality Control

Our 1-Piperazineethanol, 4-(2-(3,4-Dimethoxyphenyl)-1-(4-Methylphenyl)Ethy L)-, Dihydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and safety parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.