Description

(+/-)5,6-Epoxyeicosa-8Z,11Z,14Z-Trienoic Acid CAS NO 87173-80-6 is a specialized epoxy fatty acid derivative, specifically a 5,6-epoxide of eicosatrienoic acid. This compound serves as a critical biochemical intermediate and reference standard for research into eicosanoid metabolism and lipid signaling pathways. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and advanced life science sectors for investigating inflammation, cardiovascular function, and related biological processes.

Application

• Biochemical Research Standard: Used as a high-purity reference compound in analytical laboratories for method development and calibration in lipidomics and metabolomics studies.
• Eicosanoid Pathway Investigation: Serves as a key intermediate or substrate for studying the enzymatic activity of cytochrome P450 epoxygenases and the biological roles of epoxy-eicosatrienoic acids (EETs).
• Pharmaceutical R&D: Employed in drug discovery programs targeting pathways related to inflammation, hypertension, and angiogenesis, where EETs and their metabolites play a regulatory role.
• Cell Signaling Studies: Utilized in vitro and in vivo to elucidate the mechanisms of action of lipid-derived mediators in cardiovascular and renal systems.
• Synthetic Chemistry Building Block: Acts as a starting material or intermediate for the custom synthesis of more complex eicosanoid analogs and labeled derivatives for tracer studies.

Basic Information

Product Name	(+/-)5,6-Epoxyeicosa-8Z,11Z,14Z-Trienoic Acid
CAS No.	87173-80-6
Molecular Formula	C20H32O3
Molecular Weight	320.47 g/mol
Synonyms	5(6)-Epoxy-8Z,11Z,14Z-eicosatrienoic Acid; 5,6-EET; 5,6-Epoxy-8,11,14-eicosatrienoic Acid; (±)5,6-Epoxyeicosatrienoic Acid; 5,6-Epoxy-8Z,11Z,14Z-eicosatrienoic Acid; AA 5,6-Epoxide; Arachidonic Acid 5,6-Epoxide
EINECS	Contact for details

Quality Control

Our (+/-)5,6-Epoxyeicosa-8Z,11Z,14Z-Trienoic Acid is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 95% (Area %)
Purity (GC / HPLC)	≥ 90%
Solubility	Soluble in ethanol, DMSO, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.