Description

3-Hydroxy-2,3-Dihydrowithanolide F is a specialized withanolide derivative, a class of naturally occurring C28 steroidal lactones known for their significant biological activity. This compound is valued for its role as a key intermediate and reference standard in advanced pharmaceutical and phytochemical research. It is primarily sought by research institutions and manufacturers in the life sciences sector focusing on drug discovery, natural product chemistry, and the development of therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and building block for the synthesis and study of novel withanolide-based therapeutics.
• Natural Product Chemistry: Used as a purified marker compound for the identification, quantification, and isolation of bioactive constituents from plant extracts, particularly those from the Solanaceae family.
• Bioactivity Screening: Employed in in vitro and in vivo studies to investigate potential anti-inflammatory, immunomodulatory, and cytotoxic properties.
• Analytical Method Development: Acts as a high-purity calibrant for developing and validating analytical methods such as HPLC, LC-MS, and TLC for quality control of herbal products.
• Academic & Institutional Research: Utilized in universities and research institutes for mechanistic studies and exploring structure-activity relationships (SAR) of steroidal lactones.

Basic Information

Product Name	3-Hydroxy-2,3-Dihydrowithanolide F
CAS No.	87168-24-9
Molecular Formula	C28H38O7
Molecular Weight	486.60 g/mol
Synonyms	3-Hydroxy-2,3-dihydrowithanolide F; Withanolide derivative; (22R)-3β,27-Dihydroxy-1-oxo-ergosta-2,5,24-trien-26-oic acid δ-lactone; 3-Hydroxy-2,3-dihydro-withanolide F; 2,3-Dihydro-3-hydroxywithanolide F; 3β-Hydroxy-2,3-dihydrowithanolide F
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-2,3-Dihydrowithanolide F is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is characterized using advanced spectroscopic and chromatographic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.