Description

1-Propanamine, 3-((5-(4-Chlorophenyl)-4-Methyl-1H-Pyrazol-3-Yl)Oxy)-N, n-Dimethyl-, (R-(R*,R*))-2,3-Dihydroxybutanedioate (1:1) is a high-purity, non-racemic chiral amine salt with a complex molecular architecture, designed for advanced synthetic applications. This compound matters as a critical pharmaceutical intermediate and a versatile chiral building block for the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material science sectors seeking to incorporate sophisticated stereochemistry into their products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Research: Serves as a precursor for developing advanced, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Asymmetric Catalysis: Utilized as a chiral ligand or auxiliary in catalytic reactions to induce stereoselectivity, enabling the production of single-enantiomer compounds.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules for research and development.
• Academic & Industrial R&D: A valuable reference standard and starting material for methodological studies in organic chemistry and process development.

Basic Information

Product Name	1-Propanamine, 3-((5-(4-Chlorophenyl)-4-Methyl-1H-Pyrazol-3-Yl)Oxy)-N, n-Dimethyl-, (R-(R*,R*))-2,3-Dihydroxybutanedioate (1:1)
CAS No.	86871-75-2
Molecular Formula	C19H26ClN3O7
Molecular Weight	443.88 g/mol
Synonyms	(R,R)-Tartaric acid salt of 3-((5-(4-Chlorophenyl)-4-methyl-1H-pyrazol-3-yl)oxy)-N,N-dimethylpropan-1-amine; 3-[(5-(4-Chlorophenyl)-4-methyl-1H-pyrazol-3-yl)oxy]-N,N-dimethyl-1-propanamine (R,R)-tartrate; Dexamisole tartrate; Dexamisole (R,R)-tartrate salt; (R)-Dexamisole tartrate; Levamisole impurity/degradant reference standard; Chiral amine tartrate salt; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high enantiomeric purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, chiral chromatography, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, chiral purity, and impurity profiles. We support compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.